Carlos Frias took over for Kershaw in the top of the fourth, and walked Napoli to begin the inning. Then with one out, Uribe hit an RBI double down the third baseline to tie the game at 1-1.
Roberto Perez followed with an RBI double of his own, giving the Indians a 2-1 lead. Frias issued consecutive walks to load the bases, but got out of the jam without any further damage. Kluber retired Scott Van Slyke, Joc Pederson and Elian Herrera in order in the bottom of the fourth.
After retiring the first two batters faced in the fifth, Frias gave up a double to Marlon Byrd. The right-hander was then letdown by Pederson, who dropped an underhanded attempt at a fly ball, allowing Byrd to score.
Segedin led off the bottom half of the fifth with a gift double as Byrd slipped on the warning track in right field. Kluber got Culberson to ground out, then gave way to Jeff Manship. The Indians reliever got back-to-back strikeouts of Austin Barnes and Matt Jones.
Frias’ third inning of work was smoother than his first two, as he set the Indians down in order in the sixth. A Francisco Lindor walk and Santana base hit put runners on first and third with none out in the seventh.
Frias traded a 6-4-3 double play for a run, but couldn’t get out of the inning as he issued a two-out walk. Lisalverto Bonilla entered and walked Todd Hankins before striking out Collin Cowgill to end the inning.
Devan Ahart led off the bottom of the seventh with a double, but was caught between third base and home plate with one out on a fielder’s choice. Culberson extended the inning by drawing a two-out walk, but Barnes flied out to right field.
Thompson hit a solo home run in the eighth inning to cut the Indians’ lead in half. With the tying runners on base and one out in the bottom of the ninth, Culberson pulled an RBI single into left field. That was as close as they got however, losing to the Indians, 4-3.